We may experience pain as a prick, tingle, sting, burn, or ache. Receptors on the skin trigger a series of events, beginning with an electrical impulse that travels from the skin to the spinal cord. The spinal cord acts as a sort of relay center where the pain signal can be blocked, enhanced, or otherwise modified before it is relayed to the brain.
Pain is a complicated process that involves an intricate interplay between a number of important chemicals found naturally in the brain and spinal cord. In general, these chemicals, called neurotransmitters, transmit nerve impulses from one cell to another.
Headaches and Migraines
Strains and Sprains
- bruising
- loss of mobility at the injury site
-
swelling.
Cuts and Breaks
lower levels of serotonin
Some have speculated that lower levels of serotonin in the blood leads to lowered pain thresholds or an increased sensitivity to pain. Serotonin is a neurotransmitter in the brain. It’s associated with a calming, anxiety-reducing reaction. The lowered pain thresholds may be caused by the reduced effectiveness of the body’s natural endorphin painkillers and the increased presence of a chemical called “substance P.” Substance P amplifies pain signals.
Cancer cells
There are many causes of cancer pain, but most cancer pain occurs when a tumor presses on nerves or body organs or when cancer cells invade bones or body organs. Cancer treatments such as chemotherapy, radiation, or surgery also may cause pain.
Diagnosing the Cause of Pain
- CT or CAT scan: Computed tomography (CT) or computed axial tomography (CAT) scans use X-rays and computers to produce an image of a cross-section of the body. During the test, you will be asked to lie as still as possible on a table. The table will move through a large, donut-shaped scanning device. Sometimes, an intravenous (injected into a vein) contrast material is required for a CAT scan. In such cases, you may have a blood test before the CAT scan appointment. Most CAT scan procedures take 15-60 minutes.
- MRI: Magnetic resonance imaging produces very clear pictures of the body without the use of X-rays. This test uses a large magnet, radio waves and a computer to produce images. In most cases, an MRI takes 40 to 80 minutes, during which time several dozen images may be obtained. Certain MRI exams require an injection of a contrast material called gadolinium, which helps identify certain anatomic structures on the scan images. Due to the magnets used in the study, some people (like those who have pacemakers) should not have an MRI.
- Discography: During discography a contrast dye is injected into the spinal disc that is thought to be causing back pain. The dye outlines the damaged areas on X-rays taken following injection. This procedure is often suggested for people who are considering surgery or IDET (intradiscal electrothermal treatment).
- Myelograms: As in discography, during the myelogram procedure, a contrast dye will be injected into the spinal canal to enhance the diagnostic ability of X-ray. Doctors are able to see on X-ray the image of the spinal cord and can identify nerve compression caused by herniated discs or fractures.
- EMG: This procedure allows doctors to evaluate the activity of the muscles. During the procedure, very fine needles are inserted in muscles to measure the muscles response to signals from the brain or spinal cord.
- Bone scans: Bone scans are used to diagnose and monitor infection, fracture, or other disorders in the bone. During a bone scan, a small amount of radioactive material is injected into the bloodstream. The material will collect in the bones, particularly in areas with any abnormality. Scanner-generated images are sent to a computer to identify specific areas of irregular bone metabolism or abnormal blood flow.
- Ultrasound imaging: Also called ultrasound scanning or sonography, this test uses high-frequency sound waves to obtain images inside the body. The sound wave echoes are recorded and displayed as a real-time visual image.
